Inhibition of Wnt signaling and cancer stem cells
نویسندگان
چکیده
منابع مشابه
Inhibition of Wnt signaling and cancer stem cells
Cancer stem cells represent a small number of pluripotent and self-renewing cells within a tumor, which are resistant to conventional chemotherapy and are responsible for tumor initiation and maintenance. The Wnt/β-catenin signaling pathway drives stem cell self-renewal and is involved in the pathogenesis of various types of cancer. Aberrant activation of the Wnt signaling pathway in normal ste...
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ژورنال
عنوان ژورنال: Oncotarget
سال: 2011
ISSN: 1949-2553
DOI: 10.18632/oncotarget.309